Endocrine Abstracts

Background: Obesity is a serious health problem worldwide and is caused by a wide variety of etiologies. There are several hormones which have been proved to be associated with increased body weight and has a direct effect on the fat metabolism like thyroid hormones.Methods: This is a case control study which included 384 adult persons, they were divided into 2 groups according to the thyroid function status, the first group included 204 apparently healt...

Introduction: Significant hypoglycaemia is a rare but well recognised presenting feature of secondary adrenal insufficiency. Such hypoadrenalism may be caused by intrinsic hypothalamo-pituitary disease (pituitary adenoma), exogenous steroid therapy, and uncommonly by hypophysitis and pituitary secondaries from malignant disease.Case presentation: A 73-year-old woman presented acutely with confusion, agitation, and a...

Introduction: Significant hypoglycaemia is a rare but well recognised presenting feature of secondary adrenal insufficiency. Such hypoadrenalism may be caused by intrinsic hypothalamo-pituitary disease (pituitary adenoma), exogenous steroid therapy, and uncommonly by hypophysitis and pituitary secondaries from malignant disease.Case presentation: A 73-year-old woman presented acutely with confusion, agitation, and a...

Hyperglycaemia is common in patients (~65%) when they are admitted to hospital with ACS. It is recognised to be one of the important prognostic indicators for all-cause mortality in patients who present with ACS, regardless of pre-existing diabetes1. NICE guidelines recommend to keep blood glucose (BG) levels below 11 mmol/l2 and offer all people with hyperglycaemia after ACS (without known diabetes) for HbA1c 3 check before discharge. We were interested to see whether we foll...

31 years old lady with no past medical history or family history of thyroid disease had her first dose of Pfizer vaccine and few days later she presented unwell, Febrile with painful swelling in the neck. She was thought to have Covid because of fever. Examination revealed tender thyroid enlargement with positive bruit and Tachycardia. Investigations showed florid thyrotoxicosis with TSH: < 0.02, fT4: 60.0, CRP: 60, rest of investigation: normal, TRab and TPO AB: pending, ...

Case history: A 73-year-old gentleman was admitted for evaluation of recurrent hypoglycaemia. He has had type 1 diabetes mellitus for 60 years, which was well controlled on a basal-bolus regime with carbohydrate counting. He had frequent hypoglycaemic episodes for 5 months despite drastic reduction in insulin dosage. His insulin was completely stopped on admission. He did not develop ketosis and continued to have hypoglycaemia. He did not have end-organ complications from T1DM...

Case history: A 41-year-old lady referred to diabetes clinic due to chronic diarrhoea on Metformin and for consideration of any injectable treatment. HbA1c was 41 and BMI is 35. In 2007, OGTT during pregnancy showed fasting glucose of 4.1 mmol/l and 2 h glucose of 7.8 mmol/l. In 2013 her fasting glucose was 7.5 and HbA1c was elevated at 53 mmol/mol. Since July 2013 she has been diagnosed as type 2 DM and started on Metformin. In October 2013 HbA1c fell to 49. Over the succeedi...

We present the case of a 77-year-old woman with a medical history of diabetes mellitus type 2 and hypothyroidism who was admitted to hospital after having had episodes of recurrent symptomatic hypoglycaemia. The patient had diabetes mellitus type 2 for 26 years and this had gone into remission over the previous 2 years: she had been having recurrent hypoglycaemia necessitating reduction in insulin doses and then subsequent discontinuation of therapy altogether. There was a his...

Background and aims: It has been demonstrated that the thyroid autoimmunity, during pregnancy, adversely affects the course of the pregnancy. The anomalies may be prior to the conception, hence the interest of studying the women during the genital activity period. Our objective was to determine the prevalence of the thyroiditis in childbearing age women.Materials and methods: Prospective study, on 270 childbearing age women. Study protocol: clinical exam...

Background and aims: The hypothyroidism may be prior to the conception, hence the interest of studying women during the genital activity period. Our objective was to determine the prevalence and the etiologies of the hypothyroidism in childbearing age women.Materials and methods: Prospective study, on 270 childbearing age women. Study protocol: clinical examination, urinary iodine, thyroid stimulating hormone (TSH), free thyroxine (FT4) and thyroid antib...